and be available at the bedside. See preprinted order sheets for 
marrow reinfusion. 
c. Procedure is explained to the patient and family. 
d. All patients will have central venous access, preferably a double 
lumen catheter system. 
e. VS flow sheet at the bedside 
f. Normal saline for IV infusion 
g. Baseline vital signs are taken and recorded. 
3. Marrow Infusion 
a. After thawing rapidly in 37 “C water bath, the marrow is 
administered by the physician as rapidly as possible. A physician 
and nurse both MUST remain in the room for the total infusion 
time and 1 hr post infusion. 
NOTE: The marrow MUST NOT be FILTERED . 
b. Vital signs are taken q 15 min. x 4; Q 30 min. x 4, Q hour x 4 
and recorded. Patient is monitored by oximeter during infusion 
and for 6 hours afterward. 
t 
4. Toxicity of Infusion 
a. Volume overload: 
This is of particular importance in small recipients. 
b. Pulmonary emboli 
Rare complication that might occur due to fat and marrow cell 
emboli. Marrow and fat emboli cause a transient alveolar 
capillary block and administration of O 2 or IPPB may be neces- 
sary. 
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Recombinant DNA Research, Volume 14 
