Human Gene Thenpy Subcommittee - 4/5/91 
that more data be provided about the transduction efficiency of the neomycin resistance 
gene in human hepatocytes. Additional changes will be made in the consent form that 
will clarify the differences between the hepatocellular transplantation procedures and the 
use of the neomycin resistance gene as a marker. 
The motion passed by a vote of seven in favor, two opposed, and no abstentions. 
X. FUTURE MEETING DATES: 
Dr. Walters reminded the subcommittee that the next meeting would be on July 29, 1991 
and that the RAC meets next on May 31, 1991. 
XL ADJOURNMENT 
There being no further business. Dr. Walters then adjourned the meeting of the 
subcommittee at 4:55 p.m., on April 5, 1991. 
Nblson A. Wivel, M.D. 
Executive Secretary 
I hereby acknowledge that, to the best of my 
knowledge, the foregoing Minutes and 
Attachments are accurate and complete. 
Date: 
LeRoy B. Walters, Ph.D. 
Chair, Human Gene Therapy 
Subcommittee 
National Institutes of Health 
Recombinant DNA Research, Volume 14 
[595] 
