Recombinant DMA Advisory Committee - 5/30-31/91 
I. CALL TO ORDER AND INTRODUCTORY REMARKS: 
Dr. McGarrity, Chair, called the meeting of the Recombinant DNA Advisory Committee 
(RAC) of the National Institutes of Health (NIH) to order at 9:00 a.m., May 30, 1991. He 
said the meeting was called pursuant to a Federal Register notice which, being 30 or more days 
prior to today's date, met requirements of the NIH Guidelines for Research Involving 
Recombinant DNA Molecules. He stated that the meeting would remain open to the public 
for its entirety, and that he expected the meeting to be of two days duration. 
Dr. McGarrity noted a quorum was present and said every attempt would be made not to 
limit debate, but to keep the agenda moving, in hopes that all agenda items could be heard 
and discussed before members had to leave for travel purposes. 
Dr. McGarrity stated that the RAC was advisory to the Director of NIH and that any action 
taken by the committee was not binding on the NIH, but that Director may choose to accept, 
reject, modify or defer any recommendations or advice provided by the RAC. 
Dr. McGarrity noted that he intended to make every effort to abide by the distributed agenda 
with respect to time estimates for each item of business. He reminded the committee that in 
recognizing persons for comments he would use the following order: primary and secondary 
reviewers on each item as set forth in the agenda; other members of RAC; ad hoc consultants 
to the RAC; NIH staff members; members of the public who had submitted written 
comments; and finally, other members of the public. 
Dr. McGarrity welcomed the following new members who were attending their first RAC 
meeting: Professor John Barton, Stanford University; Dr. Constance Brinckerhoff, Dartmouth 
Medical School; Professor Alexander Capron, University of Southern California; Professor 
Roy Doi, University of California at Davis; Dr. Robert Haselkom, University of Chicago; and 
Dr. Brigid Leventhal, Johns Hopkins University. He noted that Dr. LeRoy Walters, Chairman 
of the Human Gene Therapy Subcommittee (HGTS) was also in attendance serving as an 
hoc member for this meeting of the RAC. 
Dr. McGarrity then called on Dr. Post to introduce the next agenda item. 
II. REVIEW OF THE MINUTES OF THE FEBRUARY 4, 1991 MEETING OF THE RAC: 
Dr. Post said he had reviewed the minutes and found them to be consistent with his memory 
of what had transpired at the meeting. He suggested that Drs. Rosenberg and Blaese be given 
a chance to comment on sections which dealt with their presentations to ensure that the 
description of the technical portions of their comments were correctly reported in the minutes. 
Mr. Mannix suggested several corrections of typographical errors and suggested that the Office 
of Recombinant DNA Activities (ORDA) staff could make these corrections in the final 
version of the minutes. 
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Recombinant DNA Research, Volume 14 
