Name of Conunittee 
Action Aptaroved. Rejected, or in Process 
In process 
PCI Protocol Committee 
Precise of Protocol; Patients with melanoma with evaluable disease who have 
failed standard therapy will receive treatment with Interleukin- 2 , Interleukin-4 
and tumor infiltrating lymphocytes (TIL's). When TIL's cannot be grown to 
sufficient number patients will receive IL-2 and IL-4 without adoptive transfer 
of cells. Consenting patients with tumors accessible or repeated biopsy will 
also have TIL's transduced with a marker gene. 
Recombinant DNA Research, Volume 14 
[835] 
