and Minato, N. : IL-7 promotes thymocyte proliferation and maintains 
immunocompetent thymocytes bearing alpha, beta, or gamma T-cell 
receptors in vitro : Synergism with IL-2. J. Immunol. 143:2917- 2922, 
1989. 
8. Rosenberg, S.A., Lotze, M.T. , Yang, J.C., Aebersold, P.M. , Linehan, 
W.M. , Seipp, C.A., an White, D.E.: Experience with the use of high 
dose interleukin-2 in the treatment of 652 cancer patients. Ann. 
Surg. 210:474-485, 1989. 
9. Banchereou, J.: Human interleukin-4 and its receptor. In : 
Hematological growth factors in clinical applications. Marcel 
Dekker, Inc. , in press. 
10. Mule J.J., Smith, C.A., and Rosenberg, S.A.: Interleukin-4 (B-cell 
stimulatory factor 1) can mediate the induction of lymphokine- activated 
killer cell activity directed against fresh tumor cells. J. Exp. Med. 
166:792-797, 1987. 
11. Mule, J.J., Krosnick, J.A., and Rosenberg, S.A.: IL-4 regulation of 
murine lymphokine -activated killer activity in vitro . J. Immunol. 
142:726-733, 1989. 
12. Kupper, T. , Horowitz, M. , Lee, F. , Robb, R, , and Flood, P.M. : Autocrine 
growth of T cells independent of interleukin- 2 : Identification of 
interleukin-4 (IL-4, BSF-1) as an autocrine growth factor for a cloned 
antigen- specific helper T cell, J. Immunol. 138:4280-4287, 1987. 
13. Paul, W.E. : Interleukin- 4/B cell stimulator/ factor-1: one lympho- 
kine, many functions. FASEB J. 1:456-461, 1987. 
14. O'Garra, A., Warren, D.J., Holman, M. , Popham, A.M. , Sanderson, C.J., and 
Klaus, G.G.B.: Interleukin-4 (B-cell growth factor Il/eosinophil 
differentiation factor) is a mitogen and differentiation factor for 
preactivated murine B lymphocytes. Immunology 83:5228-5232, 1986. 
15. Defrance, T. , Aubry, J.P., Rousset, F. , Vanbervliet, B. , Bonnefoy, 
J.Y., Arai, N. , Takebe, Y. , Yokota, T. , Lee, F. , Aral, K. , De Vries, 
J., and Banchereau, J.: Human recombinant interleukin-4 induces Fcg 
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