November 14, 1977 
Developmental Biology Tanel 
Comment on draft revision of the NIH Guidelines 
UNITED STATES GOVERNMENT 
memorandum 
Herman W, Lewis 
Senior Scientist for Recombinant DNA 
When considering plant systems as possible recipients of 
recombinant DNA molecules, the guidelines should distinguish between 
plant cell s 'and protoplasts. The latter are a giant step in the 
direction of biological containment since they cannot sVrviVe 
outside of the experimental situation. 
Buy U.S. Savings Bonds Regularly on the Payroll Savings Plan 
OPTIONAL. FORM NO. 10 
(RCV. 7-701 
GSA FPMR{4tCTR) 101-11* 
50UMI1 
[Appendix A — 60] 
