►UILGSAM SERVICE center 
HIODLETOwN, VA. 226«5 
uiestern union 
Mailgram’ IH 
2-005R15C320 lt/lfr/77 TWX MOANDERSON HOU *SH9 
35 HOUSTON, TEXAS tl-i<»-77 
director 
national INSTITUTES OP HEALTH 
9000 ROCKVILLE R IKE 
BEThESQA, haSylanq 20014 
IN RESPONSE TO PROPOSED REVISED GUIOElINE.5 FOR RECOMHI.nanT Dna 
RESEARCH FEDERAL REGISTER, VOL, 42, no. 187, SEPT. 27, 1977, 
PART HI — SELECTED * E R 9 E R S OF THE INSTITUTIONAL 8I0HAZAR0S 
COmh I T Tf E OF The UNIVERSITY OF TEXAS SYSTEM CANCER CENTER HAVE 
REVIEWED The REVISED GUIDELINES. -E ARE IN SURPGRT OF The 
PROPOSED REVISIONS, Th£Y ALLO* FOR APPROPRIATE DO-NGRAOING OF 
CONTAINMENT REUUIREmEnTS AS APPROPRIATE VECTORS BECOME 
aVaIL ABLE BUT RETAIN ADEQUATE SAFEGUAROS FOR ALL RESEARCH 
INVOLVING RECOMBINANT ONA. THE ROLE OF INSTITUTIONAL BIOHAZARDS 
COMMITTEES IN REVIEW OF FACILITIES, PERSONNEL, AND PROCEDURES 
SHOULD 8E RETAINED, *£. URGE EARLY ADOPTION OF Th£ REVISED 
GUIDELINES, 
ROBERT C. HICKEY, m.D, 
EXECUTIVE VICE PRESIDENT and DIRECTOR 
THE UNIVERSITY OF TEXAS SYSTEM CANCER CENTER 
HOUSTON, TEXAS 77030 
10104 EST 
MGMCOHP HGM 
[Appendix A — 73] 
StftVtCt * 
