UNIVERSITY OF COLORADO 
MEDICAL CENTER 
4200 EAST NINTH AVENUE 
DENVER, COLORADO 80262 
Box C-245 
SCHOOL OF MEDICINE 
DEPARTMENT OF PREVENTIVE MEDICINE 
AND COMPREHENSIVE HEALTH CARE 
7 June 1978 
Dr. Donald Fredrickson 
Director, NIH 
Bethesda, Maryland 20014 
Dear Dr, Fredrickson: 
The new revisions of the Guidelines for Recombinant DNA Research 
should be reviewed at a public meeting similar to the one called 
in December for the previous revision. I feel that the public 
must be involved in the decision process since they are the ones 
whose health is at stake, in case the proposed guidelines were 
inadequate. For this reason, too, a full Environmental Impact 
Statement must be developed in regard to the new revisions. 
Further, I think that authorization for experiments in this area 
should remain with the NIH, but regulation of laboratory procedures 
to protect employees and the public should be the business of OSHA 
and EPA respectively, not NIH. 
Yours sincerely 
John C. Cobb, M.D. , M.P.H 
Professor 
JCC/rt 
[Appendix A — 321] 
THE UNIVERSITY OF COLORADO IS AN EQUAL OPPORTUNITY EMPLOYER 
