42 
There are some types of research with which there is little if any 
disagreement; that is, experiments within the same species and which 
do not involve pathogens. There are experiments, prohibited by the 
guidelines ; which all agree should not be attempted until much more 
information is available, and then there are areas where there is 
uncertainty and, at least from the perspective of the researchers 
advocating the research, these should De controlled until more infor- 
mation is available; these are the areas governed by the P2-P4 types 
of experiments described in the guidelines. Here the issues center more 
on classification and less on whether the research should be conducted. 
[Appendix B — 91] 
