33 
CONGRESSIONAL BUDGET OFFICE COST ESTIMATE 
March 23,1978. 
1. Bill number H.R. 11192. 
2. Bill title : None. 
3. Bill status : 
As ordered reported by the House Committee on Interstate and For- 
eign Commerce on March 14, 1978. 
4. Bill purpose : 
A bill to extend for two years the scope of the containment require- 
ments of the experimental guidelines of the National Institutes of 
Health respecting recombinant DNA research to include all public 
and private recombinant DNA activities and to provide for a study 
respecting research and technology involving genetic manipulation. 
5. Cost estimate : 
Projected Costs 
Fiscal year 1979 : Millions 
Estimated authorization level $2.42 
Costs 2.23 
Fiscal year 19S0 : 
Estimated autrorization level 3.00 
Costs 2.95 
Fiscal year 1981 : 
Estimated authorization level 2.79 
Costs * 2.81 
Fiscal year 1982 : 
Estimated authorization level 2.15 
Costs 2.20 
Fiscal year 1983 : 
Estimated authorization level 2.30 
Costs 2.29 
Note. — The costs of this bill fall within budget function 550. 
6. Basis for estimate : 
Enactment of H.R. 11192 would extend the National Institutes’ of 
Health regulatory and experimental guidelines for recombinant DNA 
research to all public and private recombinant DNA activities. Cur- 
rently, only those activities funded by the NIH are covered. The bill 
also authorizes the creation of a commission for the study of research 
and technology involving genetic manipulation. 
The assumptions made in estimating the authorization levels of 
H.R. 11192 were: 
Approximately 200 newly covered laboratories will require 50 new 
regulatory inspectors at an average wage of $20,700 plus 70 percent 
for employee benefits, travel costs, and administrative expenses (all 
inflated in outyears by CBO’s federal wage deflator) ; and 
Creation of the study commission for the full 32 months authorized 
will require 10 members from outside the NIH at the stipulated GS- 
18 wage rate ; since there is no precedent for estimating periodic in- 
creases in salary at this level, no assumption for future salary adjust- 
ments were made ; an additional 60 percent for travel and administra- 
tive costs was added and inflated in outyear by CBO’s federal wage 
deflator. 
It is assumed that the estimated authorization levels will be fully 
appropriated at the beginning of each fiscal year. The costs are es- 
timated on the basis of a current year spendout rate of .92 and a prior 
year balance spendout rate of .08. 
[Appendix B--163] 
