28 
2-Year cost ifrojection^—H.Ji^, ftpCQtnMnant DNA Act 
[Dollars in mlllioiM] 
Number oppositions in HEW 
Projected cost, Title I 
Projected cost, Title II 
197J ( l»89 
50 ' 75 
$ 3.0 $ 4.5 
.5 .5 
These projections are based upon the current 200 labora- 
tories now using recombinant DNA techniques, and the 300 
projected by the end of fiscal year 1978. This number is 
expected to grow significantly in the near future. 
The required staff positions include those involved in de- 
veloping and conducting training programs for the approxi- 
mately 1,500 scientists and technicians soon to be involved 
in recombinant DNA research, to handle paperwork involved 
with the registration of activities, and to assist the Secretary 
and the NIH Recombinant Advisory Committee in carrying 
out its duties to develop and review safety standards and then 
respond to inquiries from the scientific community regarding 
interpretation of the regulations and from the public regard- 
ing the safety and usefulness of recombinant DNA activities, 
and' for inspectors and other general support staff. 
The estimated cost of the study commission is listed 
separately. 
INFLATION IMPACT 
The following inflation impact statement is taken directly from 
Part 1 of this report : 
The committee anticipates that the enactment of H.R. 11192 
will have a negligible impact on inflation in the biomedical 
research area and in Federal spending. As determined by the 
Congressional Budget Office, the cost to the government of 
expanding the scope of the NIH Guidelines governing re- 
combinant DNA activity to encompass all such activity re- 
gardless of its funding source would be less than $3 million 
annually. In view of the potential hazards to the public 
ii?alth and the environment from improperly conducted re- 
combinant DNA activities and the potential benefits to society 
which may derive from such activities, the minimal increases 
in expenses which may accrue to entities engaged in recom- 
binant DNA activities in connection with compliance with 
the requirements of the proposed legislation are wholly 
appropriate. 
COMMITTEE RECOMMENDATION 
A quorum being present, the bill was ordered reported by the Com- 
mittee on April 18, 1978, bv a vote of 24 ayes, 4 nays, and 12 not voting. 
ADMINISTRATION VIEWS 
The views of the Administration on H.R. 11192, as reported by the 
Committee on Interstate and Foreign Commerce, were presented dur- 
ing hearings by the Subcommittee on Science, Research and Technol- 
ogy on April 11, 1978, by Dr. Donald S. Fredrickson, Director, 
[Appendix B — 216] 
