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(2) the expiration of the detention period appli- 
cable to such order, 
whichever occurs first. 
(d) No individual designated the Secretary to con- 
duct an inspection under subsection (a) shall be required to 
obtain a search or inspection warrant from any judicial of- 
ficer before entering any place to conduct such inspection. 
(e) No individual who is engaged in or has a direct 
financial interest in a project involving a recombinant DNA 
activity may be designated by the Secretary to conduct an 
inspection under subsection (a) of such project. 
EFFECT ON STATE AND LOCAL REQUIREMENTS 
Sec. 106. (a) Except as provided in subsection (b) , 
no State or political subdivision of a State may esta 1 lish or 
continue in effect any requirement for the regulation of re- 
combinant DNA activities. 
(b) Upon application of a State or political subdivision 
of a State, the Secretary shall, by order promulgated after 
providing (in accordance with this subsection) notice and 
opportunity for an oral hearing on such application and after 
considering local conditions, exempt from subsection (a) of 
this section, under such conditions as may be prescribed in 
such order, a requirement of such State or political subdivi- 
sion applicable to recombinant DNA activities if — 
[Appendix B — 234] 
