4 
The experiment is also to be performed in the strictest 
known physical containment laboratory conditions, so as to 
prevent excape of'the results of the experiment (Slip Op. 
p. 3, Findings of.Fact p. 2, EIS p. 51). The combination 
of physical and biological safeguards to be used are 
exceptionally strict. The experiment will be conducted 
in rigorous conformance with the guidelines developed by 
N I H , and discussed in its programmatic EIS on recombinant 
DNA research (EIS p. 51-52, 55, 57-61). Mack does not 
challenge the programmatic EIS. His position is that a 
separate EIS is needed for this particular experiment. 
The programmatic EIS acknowledges the hypothetical 
risks in all recombinant DNA research (e.g., pp. 1, 23-31, 38), 
however, any such dangers are unpredictable unknowns, based 
on current knowledge, and would constitute unexpected results. 
The remote possibility of spread of harmful microbes is 
acknowledged, and the impossibility of absolute prediction 
of results is discussed (EIS pp. 23, 99, et seq . ) . There is 
a deliberate election to accept the hypothetical risks because 
disasterous results are extremely unlikely and great benefits 
are possible (EIS pp. 4-5, 89-90). The subject experiment 
is mentioned in the EIS as specifically intended and needed 
to assist in further analysis of recombinant DNA research 
(EIS p. 101). The experiment is not only contemplated in 
the EIS, it is a member of a class of contemplated experiments 
(EIS p. 82). 
[Appendix C — 26] 
