must be submitted and approved by NIH. EIS at 22. Compliance 
with the MUA is monitored by local biohazards committees. 
Id. 
In addition, NIH prepared a draft environmental 
impact statement discussing the environmental impacts of the 
Guidelines and of recombinant DNA techniques conducted under 
the Guidelines. Indeed, NIH took the unusual step of publishing 
the draft EIS in the Federal Register to insure the widest 
possible public dissemination and comment. 41 Fed. Reg. 38426 
(September 9, 1976). Public comment on the draft was voluminous. 
See Final EIS at App. K. Moreover, detailed responses to the 
comments were also made. EIS at 113. In addition to the 
extensive discussion of the Guidelines and of their environmental 
impacts, a lengthy discussion of alternatives is included. 
EIS at 65-88. Further detail is contained in the Appendices to 
the Final EIS. 
[Appendix C — 112] 
