9303-042 
9306-043 
9306-044 
9306-045 
9306-046 
9306-047 
9306-048 
(T) Boucher. Richard C. and Knowles. Michael R.. University of North 
Carolina. Chapel Hill. North Carolina: Gene Therapy for Cvstic Fibrosis 
Usin g El Deleted Adenovirus: A Phase I Trial in the Nasal Cavity. 
Date of RAC Approval; 3-2-93 
(T) Seigler, Hilliard F., Duke University Medical Center, Durham, North 
Carolina; A Phase I Trial of Human Gamma Interferon-Transduced 
Autologous Tumor Cells in Patients With Disseminated Malignant 
Melanoma. 
Date of RAC Approval: 6-7-93 
Date of NIH Approval: 9-3-93 
(T) Deisseroth. Albert B.; Kavanagh. John: and Champlin. Richard. 
University of Texas MD Anderson Cancer Center. Houston. Texas: Use 
of Modified Retroviruses to In troduce Ch emotherapy Resistance 
Sequences into Normal Hematopoietic Cells for Chemoprotection During 
the Therapy of Ova rian Canc er: A Pilot Trial. 
Date of RAC Approval: 6-7-93 
(T) Nabel, Gary J., University of Michigan Medical Center, Ann Arbor, 
Michigan; Immunotherapy for Cancer by Direct Gene Transfer into 
Tumors. 
Date of RAC Approval: 6-7-93 
Date of NIH Approval: 9-3-93 
(T) Barranger, John A., University of Pittsburgh, Pittsburgh, Pennsylvania, 
Gene Therapy for Gaucher Disease: Ex Vivo Gene Transfer and 
Autologous Transplantation of CD34( + ) Cells. 
Date of RAC Approval: 6-7-93 
Date of NIH APproval: 9-3-93 
(T) Karlsson, Stefan and Dunbar, Cynthia, NIH, Bethesda, Maryland, and 
Kohn, Donald B., Childrens Hospital Los Angeles, Los Angeles, 
California; Retroviral Mediated Transfer of the cDNA for Human 
Glucocerebrosidase into Hematopoietic Stem Cells of Patients with 
Gaucher Disease. 
Date of RAC Approval: 6-7-93 
Date of NIH Approval: 9-3-93 
(T) Galpin, Jeffrey E., University of Southern California, and Casciato, 
Dennis A, University of California, Los Angeles, California;^ 
Preliminary Study to Evaluate the Safety and Biologic Effects of Murine 
Retroviral Vector Encoding HIV-1 Genes [HIV-IT(V)] in Asymptomatic 
Subjects Infected with HIV-1. 
Date of RAC Approval: 6-7-93 
Date of NIH Approval: 9-3-93 
Recombinant DNA Research, Volume 18 
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