CONTINUATION PAGE: STAY WITHIN MARGINS INDICATED 
Principal Investigator/Program Director (Last, first, middle): 
Balia F, Lester C, Chrousos GP, Heideman RL, Poplack DG. Differences in cerebrospinal 
fluid penetration of corticosteroids: Possible relationship to the prevention of 
meningeal leukemia. J Clin Oncol 5:202-207, 1987. 
Packer RJ, Littman PA, Sposto RM, D'Angio G, Priest J, Nelson DF, Heideman R, Bruce 
DA. Results of a pilot study of hyper fractionated radiation therapy for children with 
brain stem gliomas. J Neurosurg Internat J Radiat Oncol Biol Phys 13:1647-1651 1987. 
Pendergrass TW, Milstein JM, Geyer JR, Mulne AF, Ksonik EJ, Morris JD, Heideman RL, 
Ruymann FB, Stuntz JT, Bleyer WA. Eight drugs in one day chemotherapy for brain 
tumors: experience in 107 children and rationale for preradiation chemotherapy. J 
Clin Oncol 5:1221-1231, 1987. 
Heideman RL, Balis F, Lester C, Poplack DG. Preclinical pharmacokinetics and toxicity 
of arabinosyl-5-azacytidine in the non-human primate. Cancer Res 48:4294-4299, 1988. 
Heideman RL, Cole DE, Balis FM, Sato J, Reaman GH, Packer RJ, Singher LJ, Ettinger LW, 
Gillespie A, Sam J, Poplack DG. A Phase I and pharmacokinetic evaluation of thiotepa 
in the cerbrospinal fluid and plasma of pediatric patients: Evidence for dose 
dependent plasma clearance of thiotepa. Cancer Res 49:736-741, 1989. 
Heideman RL, Gillespie A, Ford H, Reaman GH, Balis F, Tan C, Sato J, Ettinger LJ, 
Packer RJ, Poplack DG. Phase I and pharmacokinetic evaluation of fazarabine in 
children. Cancer Res 49:5213-5216, 1989. 
Heideman RL, Roth JS, Ford H Jr, Kinnard RD, Litterst CO, Kelley JA. Reverse phase 
HPLC determination and murine pharmacokinetics of arabinosyl-5-azacytosine . J Liquid 
Chromatogr 12:1613-1634, 1989. 
Blaney SM, Balis FM, Hegedus L, Heideman RL, McCully C, Murphy RF, Kelley JA, Poplack 
DG. Pharmacokinetics and metabolism of cyclopentenyl cytosine (CPE-C) in nonhuman 
primates. Cancer Res 50:7915-7919, 1990. 
Tobias JD, Heideman RL. Primary central hyperventilation in a child with brainstem 
glioma: Management with continuous infusion Fentanyl. J Pediatr 88:818-820, 1991. 
Relling MV, Ayers D, Heideman RL, Evans WE. Acute hematologic effects of Mephenytoin 
as a phenotyping probe. Pharmacogenetics 1:42-49, 1991. 
Fontanesi J, Golden EB, Cianci PC, Heideman RL. Treatment of radiation induced optic 
neuropathy in the pediatric population. J Hyperbaric Med 6:245-248, 1991. 
Kellie SJ, Kovnar EH, Kun LE, Horowitz ME, Heideman RL, Douglass EC, Langston JW, 
Sanford RA, Jenkins JJ, Faircloigh DL, Ogle L. Neuraxis dissemination in pediatric 
brain tumors. Cancer 69:1061-1066, 1992. 
Heideman RL, Gillespie A, Horowitz M, Balis F, Packer RJ, Reaman GH, Allen J, Lange B, 
Kovnar E, Steinberg S, Poplack DG. A Phase II Evaluation of Thiotepa in Pediatric 
Central Nervous System Malignancies. Cancer (in press), 1993. 
Pratt CB, Douglass EC, Kovnar EH, Heideman RL, Kun LE, Kellie SJ, Avery L. Phase I 
study of if osf amide given on alternate days to treat children with brain tumors. 
Cancer (in press), 1993. 
Gajjar AJ, Heideman RL, Kovnar E, Douglass EC, Langston JW, Sanford RA, Jenkins JJ, 
Kun LE. Pediatric low grade gliomas: reponse to chemotherapy. Pediatr Neurosurgery (in 
press ) , 1993 . 
Khatib Z, Heideman RL, Kovnar EH, Douglass EC, Langston JW, Sanford RA, Jenkins JJ, 
Kun LE. Dorsally exophytic brain stem tumors with pilocytic histology: A distinct 
clinicopathologic entity. Pediatr Neurosurgery (in press), 1993. 
PHS 398 (Rev. 9/91) Page — 
Number pages consecutively at the bottom throughout the application. Do nor use suffixes such a Re<30mbinant DNA Research, Volume 18 
