Recombinant DNA Advisory Committee - 12/2-3/93 
XII. Discussion on Informed Consent Issues/Dr. Ellis 27 
XIII. Addition to Appendix D of the NIH Guidelines Regarding a Human 
Gene Transfer Protocol Entitled: An Open Label, Phase I /I I 
Clinical Trial to Evaluate the Safety and Biological Activity 
of HIV-IT(V) (HIV-1 IIBenv /Retroviral Vector) in HTV-1 Infected 
Subjects/ Dr. Haubrich 29 
XIV. Addition to Appendix D of the NIH Guidelines Regarding a Human 
Gene Transfer Protocol Entitled: A Phase I Trial of B7 -Transfected 
Lethally Irradiated Allogeneic Melanoma Cell Lines to Induce Cell- 
Mediated Immunity Against Tumor-Associated Antigens Presented 
by HLA-A2 or HLA-A1 in Patients with Stage IV Melanoma /Dr. Sznol 32 
XV. Addition to Appendix D of the NIH Guidelines Regarding a Human 
Gene Transfer Protocol Entitled: Phase I Study of Immunotherapy 
of Advanced Colorectal Carcinoma by Direct Gene Transfer into 
Hepatic Metastases/Dx. Rubin 36 
XVI. Update on Dr. Roth's Protocol Entitled: Clinical Protocol for 
Modification of Oncogene and Tumor Suppressor Gene Expression 
in Non-Small Cell Lung Cancer #9209-03 1/Dr. Roth 38 
XVII. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene 
Transfer Protocol Entitled: Adoptive Immunotherapy of Melanoma 
with Activated Lymph Node Cells Primed In Vivo with Autologous Tumor 
Cells Transduced with the IL-4 Gene/ Dr. Chang 40 
XVm. Update on the Human Gene Transfer Protocol Entitled: A Phase 
I Study, in Cystic Fibrosis Patients, of the Safety, Toxicity, and 
Biological Efficacy of a Single Administration of a Replication 
Deficient Recombinant Adenovirus Carrying the cDNA of the Normal 
Human Cystic Fibrosis Transmembrane Conductance Regulator Gene in 
the Lung/Dr. Crystal 43 
XIX. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene 
Transfer Protocol Entitled: Gene Therapy for Cystic Fibrosis 
Using Cationic Liposome Mediated Gene Transfer: A Phase I 
Trial of Safety and Efficacy in the Nasal Airway /Drs. Sorscher and Logan .... 44 
XX. Addition to Appendix D of the NIH Guidelines Regarding a Human Gene 
Transfer Protocol Entitled: Adenovirus-Mediated Gene Transfer of 
CFTR to the Nasal Epithelium and Maxillary Sinus of Patients with 
Cystic Fibrosis /Dr. Welsh 47 
Recombinant DNA Research, Volume 18 
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