FF 
Principal Investigator/Program Director (Last, ri/st middle): 
BIOGRAPHICAL SKETCH 
Give the following information for the key personnel and consultants and collaborators. Begin with the principal 
investigator/program director. Photocopy this page for each person. 
NAME 
POSITION TTTLE 
Robert/E. Sobol, M.D. 
Adjunct Associate Member 
EDUCATION (Begin with baccalaureate or other Initial professional education, such as nursing, and Indude postdoctoral training.) 
INSTITUTION AND LOCATION 
DEGREE 
YEAR 
CONFERRED 
HELD OF STUDY 
Boston University, Boston, MA 
B.A. 
1974 
Philosophy 
Chicago Medical School, Chicago, IL 
M.D. 
1979 
Medicine 
RESEARCH AND PROFESSIONAL EXPERIENCE: Concluding with present position, fct, in chronological order, previous employment, experience, and 
honors. Key personnel Indude the principal Investigator and any other indMduab *bo participate fn the sctentfflc development or exoartto 
Key persomel typically wffl Indude afl intfivlduais %vfth doctoral or other professional degrees, but In some projects win indudolncfivfduals at the masters or 
baccalaureate level provided they contrRxite In a substantive way to tha scientific development or execution of the project Irfdude present membership on 
any Federal Government pubGc advisory committee. List, In chronological order, the Wes, al authors, and complete references to afl publcaflons during the 
past three years and to representative earfier pobOcatfons pertinent to thb application. DO NOT EXCEED TWO PAGES. 
Professional Experience 
1979- 1980 
1980- 1982 
1982- 1983 
1983- 1990 
1986-1989 
1990- 1992 
1991- Present 
Internship, Internal Med, University of Southern California Medical Center, Los Angeles, 
California 
Research Fellow in Hematology/Oncology, University of California, San Diego, San Diego, 
California 
Assistant Research Immunologist, U.C.S.D. Cancer Center, University of California, San 
Diego, San Diego, CA 
Associate Physician, University of California, U.C.S.D. Cancer Center, University of 
California, San Diego, San Diego, CA 
Resident, Internal Medicine, Mercy Hospital, San Diego, California 
Clinical Fellow in Hematology/Oncology, U.C.S.D. Cancer Center, University of 
California, San Diego, San Diego, CA 
Adjunct Associate Member, San Diego Regional Cancer Center • 
Publications (Partial list of 65 publications) 
1. Sobol RE, Dillman RO, Smith JD, et al: Phase I evaluation of murine monoclonal anti-melanoma 
antibody in man: Preliminary observations. Hybridomas in Can cer Diagnosis and Treatment- 
Mitchell MS, Oettgen HF (eds). Raven Press, New York, Prog Cancer Research Thor 21:199-206, 
1982. 
2. Sobol RE, Royston I, LeBien TW, et al:. Adult acute lymphoblastic leukemia phenotypes defined by 
monoclonal antibodies. Blood 65:730-735, 1985. 
3. Sobol, RE, Dillman RO, Collins H, ct al: Applications and limitations of peripheral blood 
lymphocyte immu noglobulin li gh t chain analysis in the evaluation of non-Hodgkin's lymphoma. 
Cancer 56:2005-2010, 1985. 
4. Royston I, Sobol RE: Monoclonal antibody immunocytology: Potential applications for staging and 
monitoring malig nant disease activity. J Clin One 3:455-461. 
5. Sobol RE, Mick R, LeBien TW, et al: The reproducibility of acute lymphoblastic leukemia 
phenotype determinations: Evaluation of monoclonal antibody and conventional hematopoietic 
markers. LeukRes 10:481-485, 1986. 
-is 398 (Rev. 9/9i) (Form Page 6) Page Recombinant DN A Research, Volume 18 
imber pages conse<^^f£^t the bottom throughout tte application. Do not uso suffixes such as 3a. db. 
