CONTENTS 
Federal Register of September 20, 1984, announcing proposed 
actions to be considered at meeting of the Recombinant CNA 
Advisory Committee (RAC) October 29, 1984 1 
Minutes of the Subgroup of the RAC Working Group on Human 
Gene Therapy meeting, September 26, 1984 4 
Minutes of the RAC Working Group on Release into the 
Environment meeting, October 5, 1984 11 
Minutes of the RAC Working Group on Human Gene Therapy 
meeting, October 12, 1984 89 
Minutes of the RAC meeting, October 29, 1984 131 
Minutes of the RAC Working Group on Release into the 
Environment meeting, October 30, 1984 176 
Minutes of the RAC Working Group on Human Gene Therapy 
meeting, November 16, 1984 215 
Federal Register of November 23, 1984, promulgating actions 
recommended at the RAC meeting, June 1, 1984 253 
Federal Register of November 23, 1984, revised NIH 
Guidelines 262 
Federal Register of January 22, 1985, reguesting public comment 
on Points to Consider in the Design and Submission of Human 
Somatic-Cell Gene Therapy Protocols 289 
Minutes of the RAC Working Group on Release into the 
Environment meeting, February 11, 1985 296 
Minutes of the RAC Working Group on Biotechnology Coordination 
meeting, March 1, 1985 331 
Federal Register of March 11, 1985, describing recommendations 
made at the RAC meeting, October 29, 1985, and promulgating one 
action 426 
Selected letters and documents received in the period September 
1984 to March 1985 relevant to the NIH Guidelines 435 
Index of letters and documents 572 
[v] 
