Attachment III - Page 3 
for adequate understanding of the construct. Explain the advantages 
(and disadvantage (s ) , if appropriate) of your vectors, if other 
candidate vectors could be considered. 
"3. If microorganisms cure used to introduce vectors or are vectors 
themselves, indicate hew they compare with wild-type strains. If 
disabled pathogens are used to transmit the vector, indicate factors 
that will most likely prevent these microorganisms from regaining 
or acquiring pathogenic potential. If the vector is likely to 
survive independently of the desired hosts (s), refer to this possi- 
bility, and provide any available data to assess the probability 
of such transfer to other organisms. 
"4. If microorganisms are used to introduce vectors, the absence of these 
microorganisms in the plants to be released in the field should 
be documented. 
"C. Characteristics and Monitoring of Genetically Engineered and 
Control Plants. 
"1. Provide data frem greenhouse and/or grewth chamber studies to support 
prospective field studies. Data should include morphological data 
for at least two generations of plants as appropriate. Supply any 
molecular or physiological data, especially as applicable to the 
trait(s) under consideration. 
Specify plant monitoring procedures; frequency; types of data to 
be obtained. 
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