Attachment XIV - Page 5 
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To this end, the no modi tied and modified organisms should be compared and 
contrasted with respect to the following characteristics, vhere possible 
and appropriate: 
A. Habitat and dispersal 
Kncwn and predicted environmental conditions vhich affect survival, 
multiplication, and dissemination. 
B. Biological interactions including (where appropriate): 
1. Pathogenicity, infectivity (acute or chronic), toxicity, virulence, 
colonization, or pathogen vector in animals, plants, or microorganisms. 
2 . Host range 
3. Known or predicted effects on other organisms in the environment 
including effects on competitors , prey, hosts, symbionts, predators, 
parasites, and pathogens. 
4. Known or predicted involvement in biogeochemical processes (e.g., 
mineral cycling, cellulose and lignin degradation, nitrogen fixation). 
5. Likelihood of post-release evolutionary shifts in these biological 
interactions . 
6. Likelihood of exchange of genetic information between the modified 
organism and other organisms in nature. 
IV. Trials to be Conducted 
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