20 
range more frequently than others. Whether the parental organism shifts hosts 
rapidly should be known, and this information should be included in the proposal. 
Dr. Miller said phenotypic stability is an important consideration. 
The working group agreed to accept Section III-B-5 as follows: 
"Genetic and phenotypic stability of the organism in the environment. " 
Dr. Lacy moved that the working group accept Section III of the document as modified. 
Ey a vote of ten in favor, none opposed, and no abstentions, the working group 
accepted the motion. 
| Dr. McGarrity indicated to the working group that the meeting would soon adjourn; 
i he asked if any pertinent considerations should be raised before adjournment. 
Dr. Gottesman suggested the two sentences discussed earlier by the working 
group should be retained for consideration at the next working group meeting. 
These two sentences read as follows: 
"1. Information on all these points will not be necessary in all cases, but 
will depend on the properties of the parental organism and the effect of 
the modification on these properties. 
"2. Approval of small-scale field tests will depend upon the results of 
laboratory and greenhouse testing of the properties of the modified 
organism and the known properties of the nonmodified organism. We 
anticipate that monitoring of small-scale field tests will provide 
data on environmental effects of the modified organism. Such data 
nay be a necessary part of the consideration of requests for approval 
of larger scale tests and commercial applications . " 
Dr. Gottesman moved that the working group accept the first of these proposed 
sentences as part of the preamble. Dr. Pramer seconded the motion. By a vote 
of nine in favor, none opposed, and no abstentions, the working group accepted 
the motion. 
Dr. Arntzen nominated Drs. Lacy and Tolin to attempt to construct language for 
Section V of the document. 
[Executive Secretary's Note: The document generated at the October 30, 1984, 
meeting of the Working Group on Release into the Environment is appended to 
these minutes as Attachment IV. ] 
Dr. McGarrity suggested the working group plan to meet again before the next RAC 
meeting. The working group agreed, and Dr. Mi lews ki said ORDA would arrange a 
meeting date. 
Dr. Gottesrran moved that the meeting adjourn at 4:45 p.m. on October 30, 1984. 
[197] 
