Attachment IV - Page 4 
4 
in the donor and in the modified organism(s). For the following points, 
provide information where possible and appropriate on the nonmodi fied 
organism and a prediction of any change that may be elicited by the 
modification. 
A. Habitat and Geographic Distribution 
B. Physical and Chemical Factors which can Affect Survival, Reproduction , 
and Dispersal 
C. Biological Interactions 
1. Host range. 
2. Interactions with and effects on other organisms in the environment 
including effects on competitors, prey, hosts, symbionts, predators, 
parasites, and pathogens. 
3. Pathogenicity, infectivity, toxicity, virulence, or carrier of 
pathogens. 
4. Involvement in biogeochemical or in biological cycling processes 
(e.g., mineral cycling, cellulose and lignin degradation, nitrogen 
fixation, pesticide degradation). 
5. Frequency with which populations undergo shifts in important ecolog- 
ical characteristics such as those listed in Section III above. 
6. Likelihood of exchange of genetic information between the modified 
organism and other organisms in nature. 
[ 209 ] 
