6 
Dr. Miller agreed with Dr. Mazza. He suggested the tone of the second sentence, 
if this sentence is retained in the section, should be less imperative. 
Drs. Vidaver and Tolin felt the concept that artificial environments are not 
necessarily simulants of natural environments should be reiterated in Section 
V since this section is the most important section of the document. 
Dr. Gottesman suggested the first sentence of Section V be deleted. The clause, 
"However, field testing must not be undertaken" of the second sentence should 
also be deleted. Dr. Gottesman reiterated that in some cases some risk might 
be acceptable in view of large benefits. If the working group concludes sane 
risk exists, the working group might impose additional controls in the field 
test. 
Dr. Sharpies said the working group wishes to know whether or not the proposed 
field test might present a risk; the language of the second sentence should 
reflect this desire. 
Dr. Fedoroff suggested the words "risk of environmental damage" should be 
substituted for the words "environmental risk." 
Dr. Gottesman suggested the word "risks" in the third sentence be modified by 
the word "possible." 
Dr. Colwell suggested the fourth Sentence read as follows: 
"The issues addressed might include, but not be limited to, the 
following : " 
Dr. Gottesman moved that the working group accept three sentences modified 
as follows: 
"Results of testing in artificial contained environments together 
with careful consideration of the genetics, biology, and ecology 
of the nonrrodified and the modified organisms will enable a reasonable 
prediction of whether or not significant risk of environmental 
damage will result from the release of the modified organism in the 
small-scale field test. In this section, the information requested 
in Sections II, III and IV should be sunmarized to present an analysis 
of possible risks to the environment in the test as it is proposed. 
The issues addressed might include but not be limited to the following 
items : " 
By a vote of eleven in favor, none opposed, and one abstention, the working 
group accepted the proposed language. 
Dr. McGarrity called the attention of the working group to Section V-A-l of 
Section V-A, The Nature of the Organism . Section V-A-l reads as follows : 
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