Attachment V - Page 4 
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organism and a prediction of any change that may be elicited by the 
modi ^ication. 
A. Habitat and Geographic Distribution 
P. Physical and Chemical Factors which can Affect Survival, Reproduction, 
and Dispersal 
C. Biological Interactions 
1 . Host range . 
2. Interactions with and effects on other organisms in the environment 
including effects on canpetitors , prey, hosts, symbionts, predators, 
parasites, and pathogens. 
3. Pathogenicity, infectivity, toxicity, virulence, or as a carrier 
(vector) of pathogens. 
4. Involvement in biogeochemical or in biological cycling processes 
(e.g., mineral cycling, cellulose and lignin degradation, nitrogen 
fixation, pesticide degradation). 
5. Frequency with vhich populations undergo shifts in important ecolog- 
ical characteristics such as those listed in III-C points 1 through 
4 above. 
6. Likelihood of exchange of genetic information between the modified 
organism and other organisms in nature. 
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