I. CALL TO ORDER AND INTRODUCTORY REMARKS 
Mr. Mitchell, Chair, called the meeting of the Recombinant DNA 
Advisory Committee (RAC) of the National Institutes of Health 
(NIH) to order at 9:00 a.m. , February 2, 19 87 . He said the 
meeting was called pursuant to Federal Register notice of 
December 19, 1986, which being 30 or more days prior to today's 
date met the NIH Guidelines for Research Involving Recombinant 
DNA Molecules requirements. He stated that the meeting would 
remain open to the public for its entirety, and that he expected 
the meeting to adjourn at approximately 4:00 p.m. 
Mr. Mitchell noted that with new appointments the RAC now was at 
full membership with 25 members and requested Dr. Gartland to 
ascertain whether a quorum was present. Dr. Gartland stated that 
a quorum was present, and Mr. Mitchell declared that the 
committee could proceed with business. 
Mr. Mitchell noted that he intended to make every effort to abide 
by the distributed agenda with respect to time estimates for each 
item of business and added there were four items on the agenda 
which, having been duly published in the Federal Register 30 or 
more days prior to the meeting date, the RAC could take official 
action on at this meeting. 
He then reminded the committee that in recognizing persons for 
canments he would use the follo/ing order: primary and secondary 
reviewers on each item as set forth in the agenda; other members 
of RAC; ad hoc consultants to the RAC; NIH staff members; members 
of the public who had submitted written documents; and finally, 
other members of the public. He underlined that RAC was advisory 
to the Director of NIH and that in light of this persons with 
minority opinions should voice then so as to provide Dr. 
Wyngaarden with the entire spectrum of RAC 'opinions on a given 
topic. Mr. Mitchell then told the committee that in all voting 
he would call first for the affirmative, then for the negative, 
and finally for abstentions, and underlined that if any voting 
member felt compelled to abstain due to conflict of interest that 
such member should notify the Chair so that the record could duly 
reflect such. 
Mr. Mitchell then made note of Mailings I and II which were sent 
to members prior to the meeting. He also noted that materials 
that had been recently received were supplied at the table for 
each member. 
Mr. Mitchell then introduced three new members of RAC who were 
present at the meeting: Mr. Donald C. earner. Dr. Don Bert 
Clewell, and Dr. Robert P. Erickson. He briefly outlined each 
new member's background and affiliations and stated that he and 
other members of the committee welcomed them and looked forward 
to their contributions on the committee. 
[ 168 ] 
Recombinant DNA Research, Volume 1 1 
