NOTICES 
49609 
Rabies viru s — all strains except Rabtes street 
pints, which should be classified in Class 
• when Inoculated Into carnivores 
Reodruxe* — all types 
Respiratory syncytial virus 
Rhinovlruses — all types. 
Rubella pints. 
Simian pi ruses — all types except Herpesvirus 
simiae i Monkey B virus) and Marburg 
virus, which are In Class 4 
Sindblts virus. 
Tensaic pints. 
Turlock pints 
Vaccinia pints. 
Varicella virus. 
Vole rickettsia 
Yellow /ever virus, 17D vaccine strain. 
C. Class' J agents 
1. Bacterial agents: 
Actino bacillus mallei.* 
Bartonella — all species. 
Brucella — all species 
Francisella tularensis. 
Mycobacterium a Pirn. M bovis. M tubercu- 
losis 
Pasteurella multocide type B ("buffalo" and 
other foreign virulent strains*). 
Pseudomonas pseudo mallei* 
Yer tenia pestis 
3- Fungal agents: 
Coccidioides Immitis 
Histoplasma capsulatum. 
Histoplasma capsulatum var. dubotsii 
3 Parasitic agents Schistosoma mansonl 
4. Viral, rickettsial, and chlamydial agents: 
A las trim. Smallpox. Monkey par. and While- 
par. when used in pitro. 
Arboviruses — all strains sxcept those In Clara 
3 and 4 (Arboviruses Indigenous to the 
United States are In Class 3. except those 
listed In Class a West Nile and Semltki 
Forest viruses may be classified up or 
down, depending on the conditions of use 
and geographical location of the labora- 
tory). 
Dengue virus, when used for transmission or 
animal Inoculation experiments. 
Lymphocytic chorimeningitis virus (LCM) 
Psittocosis-Ornithosis-Trachoma group of 
agents 
Rabies street virus, when used In Inocula- 
tions of carnlvorm (8ee Clara a). 
Rickettsia — all spectra sxcept Vole rickettsia 
when used for transmission or animal In- 
oculation experiments. 
Vesicular stomatitis virus.* 
Yellow /ever virus — wild, when used In vitro. 
* USDA permit also required for Import 
or Interstate transport. 
D. Class 4 agents 
1. Bacterial agents: None, 
a. Fungal agents: None. 
3 Parasitic agents: None. 
4. Viral, rickettsial, and chlamydial agents: 
Alastrim. Smallpox, Monkey pox. and White- 
par. when used for transmission or animal 
Inoculation experiments. 
Hemorrhagic /ever agents, Including Crimean 
hemorrhagic /ever (Congo). Junln, and 
Muchupo viruses, and others as yet unde- 
fined 
Herpesvirus simiae (Monkey B virus) . 
Lassa virus. 
Marburg virus. 
Tick- borne encephalitis virus complex, In- 
cluding Russian spring-summer encepha- 
litis. Kyasanur forest disease. Omsk hemor- 
rhagic /ever, and Central European en- 
cephalitis viruses. 
Venesuelan equine encephalitis virus, epi- 
demic strains, when used for transmission 
or animal Inoculation experiments. 
Yellow /ever virus — wild, when used for 
transmission or animal Inoculation ex- 
periments 
II. Classification o/ Oncogenic Viruses on the 
Basis o/ Potential Hazard ( i ) 
A. Low risk oncogenic viruses 
Rous Sarcoma. 
SV-40 
OSLO 
A7-8V40, 
Polyoma. 
Bovine papilloma. 
Rat mammary tumor. 
Avian Leukosis. 
Murine Leukemia. 
Murine Sarcoma. 
Mouse mammary tumor. 
Rat Leukemia 
Hamster Leukemia. 
Bovine Leukemia. 
Dog Sarcoma 
Maaon-Pflxer Monkey Virus. 
Merck's. 
Guinea pig Herpes 
Lucks (Prog) . 
Adenovirus. 
Shops Fibroma. 
Shops Papilloma. 
B Moderate risk oncogenic viruses 
Ad3-SV40. 
FeLV 
HV Salmtrt 
EBV. 
SSV-l. 
OaLV. 
HV atelea. 
Vaba. 
FeSV. 
III. Animal Pathogens ( 3 ) 
A. Animal disease organisms which are for- 
bidden entry into the United States by 
law (CDC Class S agent ) 
1. Foot and mouth disease virus. 
B Animal disease organisms and vectors 
which are forbidden entry info the 
United States by USDA Policy ( CDC Class 
5 agents) 
African horse sickness virus. 
African swine fever virus. 
Besnoitia besnoiti. 
Borne disease virus. 
Bovine Infectious petechial fever. 
Camel pox virus. 
Ephemeral fever virus. 
Fowl plague virus. 
Ooat pox virus. 
Hog cholera virus. 
Louplrtg 111 virus. 
Lumpy skin disease virus. 
Nairobi sheep discuss virus. 
Newcastle disease virus (Asiatic strains). 
Mycoplasma mycoides (contagious bovine 
pleuropneumonia) . 
Mycoplasma agalactlae (contagious agalac- 
tia of sheep) . 
Rickettsia ruminafium (heart water). 
Rift valley faver virus. 
Rinderpest virus. 
Sheep pox virus 
8 wine vesicular disease virus. 
Teschen disease virus. 
Trypanosoma door ( Nag ana) . 
Trypanosoma ei’ansi. 
Thelleria parva ( East Coast fever) . 
Theileria annulafa. 
Theileria lawrence i. 
Thelleria bovis. 
Theileria hirci. 
Vesicular exanthema virus. 
Weaselsbron disease virus. 
Zyonema /arciminosum (pseudofarcy.) 
Rotsences 
1 Classification o/ Stiologic Agents on the 
BaJi# of Hazard (4th Edition. July 1974). 
U.8 Department of Health, Education, and 
Welfare Public Health Service. Center for 
Disease Control. Office of Biosafety. Atlanta. 
Oeorgla 30333 
2 National Cancer Institute Safety Stand- 
ards /or Research Involving Oncogenic Vi- 
ruses (October 1974). U.8. Department of 
Health. Education, and Welfare Publication 
No (NIH) 78-790. 
8. 0 8 Department of Agriculture, Animal 
and Plant Health Inspection Service. 
(FR Doc.77-37849 Filed 9-30-77,8:48 am) 
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