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Also enclosed is a copy of the current Guidelines, a copy of the proposed 
revised Guidelines, a background paper on the proposed revision of the 
Guidelines, a roster of the Committee, an agenda for the meeting and 
the Environmental Impact Statement. 
You will notice that the agenda is structured to allow comments on each 
section of the proposed revisions; however, it is not necessary for you 
to comment on every section. When you have decided which sections 
you would like to address, please notify Dr. Charles McCarthy, Execu- 
tive Secretary of the Committee, so that we can schedule your remarks. 
Dr. McCarthy can be reached at (301) 496-1480, or National Institutes of 
Health, Building 1, Room 201, Bethesda, Maryland 20014. 
Your travel expenses will be provided under a personal services contract. 
Ms. Roberta Garfinkle will handle the necessary arrangements for the 
meeting including hotel reservations. She can be reached at (301) 496-1480. 
Let me say again that I appreciate your cooperation in this important 
matter. 
Sincerely yours. 
/s/ 
Enclosures 
Donald S. Fredrickson, M. D. 
Director 
