147 
MR. HUTT: Have you done that? 
DR. TOOZE : No, this is something that we have proposed. It is not a 
simple task, but it is something which — Dr. Fredrickson, and I am grateful 
to him, very quickly reproduced that Telex we sent, and it is amongst one 
of the sections. 
MR. HUTT: Well, what I am not clear on is how you do handle those is- 
sues at this time. 
DR. TOOZE: Well, we would get together, say, a dozen medical virolo- 
gists plus molecular virologists, and perhaps slightly more than that, to sit 
down and try and work out a reasonable proposal, virus group by virus group, 
just as these Guidelines evolved. 
MR. HUTT: What is happening today in terms of that research in Europe? 
Is it going on, and if so, under what guidelines, or under no guidelines? 
DR. TOOZE: Virus research? Virus cloning? Well now, it goes on under 
the individual national guidelines. I mean, in France, Tiollais and Philip- 
son have cloned part of the gene of adeno. 
MR. HUTT: Is there a group in France that has approved that research? 
DR. TOOZE: Yes. 
DR. FREDRICKSON: Why don't you just explain about the GMAGs? 
DR. TOOZE: Well, in each country there are national advisory commit- 
tees, but the countries are smaller and the problem is smaller, because the 
number of groups per country is much smaller. They have roughly parallel 
guidelines, but they are not identical. And for most countries — for virus 
cloning it is true in all countr ies--you must individually put your proposal 
to your national committee and have some decision made upon it. 
MR. HUTT: All right, so the procedure is an advisory committee looks 
at an individual experiment and decides that the risk is acceptable or not. 
DR. TOOZE: For virus cloning, yes. 
MR. HUTT: For virus cloning. Thank you. I am sorry to have dragged 
that out, but I thought it was useful for us to understand procedures that 
it is handled under elsewhere. 
DR. FREDRICKSON: Mr. Helms, I would guess, wants the answer to his 
earlier question, about when will all this information be available that you 
referred to earlier, Dr. Tooze. 
DR. TOOZE: Which information? 
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