185 
DR. FREDRICKSON: Are there other final questions or comments from the 
Committee? 
If not, then ladies and gentlemen, you have been extraordinarily pa- 
tient with us all. Before you go I must read you, however, one piece of 
information which refers back to a comment made rather tangentially by Mr. 
Dach and which you will probably find in your morning newspaper. That is 
that on December 14 — that is, yesterday--a letter, which I shall read to 
you, was sent to the Harvard Medical School. 
It reads, "On December 9 the National Institutes of Health received a 
proposed Memorandum of Understanding and Agreement (MUA) dated November 2 
for research grant number GM-so-and-so , Dr. Charles A. Thomas, Jr., princi- 
pal investigator. Based on information developed by an NIH site visit team 
which visited Harvard Medical School on December 12, NIH is withholding ap- 
proval of this MUA pending clarification of prior compliance by this investi- 
gator with the NIH Guidelines for Research Involving Recombinant DNA Mole- 
cules. In the absence of an approved MUA, recombinant DNA experiments sup- 
ported by NIH funds under grant number so-and-so must not be carried out. 
You will shortly receive a revised Notice of Grant Award indicating that 
funds from grant so-and-so may not be used to conduct recombinant DNA 
experiment s . " 
Several NIH program officials did visit the laboratory of Dr. Thomas, 
and the committee and the Dean at Harvard Medical School, and they will pay 
another visit to that institution, and until they do we really have not 
much more to report to you. But since you will probably be seeing this in 
the Post before you come to tomorrow's meeting, I thought I would give you 
this advance notice. 
The meeting will begin promptly tomorrow morning in this same room at 
9:00 a.m., and I wish you all a good night. 
Thank you. 
(Thereupon, at 10:25 p.m. , a recess was taken until 9:00 a.m. the next 
day. ) 
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