NOTICES 
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National Inttifvtot of Hoalth 
ADVISORY COMMITTU TO THE DIRECTOR. NIH 
MaaMnf 
Pursuant to Pub. L. 92-463, notice is 
hereby given of the meeting of the Ad- 
visory Committee to the Director. 
NIH. December 15-16. 1977. National 
Institutes of Health. Building 31. Con- 
ference Room 6C. The meeting will 
take place from 9 a.m. to 9 p.m. on De- 
cember 15. and from 9 a.m. to 5 p.m. 
on December 16. The entire meeting 
will be open to the public. 
The purpose of the meeting will be 
to consider proposed revised Guide- 
lines for recombinant DNA molecule 
research conducted and supported by 
the NIH. The proposed Guidelines 
were published in the Federal Regis- 
ter September 27. 1977. on pages 
49596 to 49609. Attendance by the 
public will be limited to space avail- 
able. 
In addition to current members of 
the Committee, a number of other sci- 
entific and public representatives have 
been Invited to serve on the Commit- 
tee for this public hearing. Ln order to 
ensure careful review, selected wit- 
nesses from the following areas will be 
invited to comment on the Guidelines 
at the hearing: environmental, com- 
mercial. organized labor, and scientif- 
ic. 
Other witnesses who wish to make 
oral statements concerning the pro- 
posed revisions to the Guidelines will 
be provided reasonable opportunity to 
do so at appropriate times Indicated 
on the agenda. All witnesses are re- 
quested to confine their comments to 
the proposed revisions. Persons who 
wish to make oral statements should 
notify the Executive Secretary of 
their intention to speak and the Sec- 
tion of the proposed revisions to which 
they will direct their comments. 
Travel expenses will be provided for 
Invited witnesses only. 
Written comments on the proposed 
revised Guidelines should be addressed 
to: Director, National Institutes of 
Health, 9000 Rockville Pike. Bethesda. 
Maryland 20014. The Executive Secre- 
tary. Charles R. McCarthy. Ph.D., Na- 
tional Institutes of Health. Building 1. 
Room 201, Bethesda, Maryland 20014 
(301) 496-1480, will furnish rosters of 
Committee members and guests, and 
substantive program information. 
The tentative agenda for the meet- 
ing is as follows: 
PaorosED Agenda roa Meeting or the Advi- 
sory COMMITTTEE TO THE DIRECTOR, NTH. 
December 15-16, 1977 
Thumdat, December 15 
9 am.— Opening remarks— Dr. Fredrickson. 
Discussion or sections or revised DNA 
guidelines 
9:30 am.— Introduction to revised guide- 
lines— Dr. Littlefield. 
Section I. Physical Containment 
Dr. Barkley 
10 am.— Comments by Invited witnesses. 
10:30 a m.— Coffee break. 
10:45 am.— Comments by other witnesses. 
11:30 am.— Section II. Biological 
Containment 
Dr. Gottesm&n 
11:45 am.— Comments by Invited witnesses. 
12:30 pm.— Comments by other witnesses. 
1 p.m.— Lunch. 
2:15 pm— Section III. Experimental 
guidelines 
Drs. Hellnskl. Rowe, and Day 
2:45 p.m.— Comments by Invited witnesses. 
3:30 pm— Coffee break. 
3:45 p.m.— Comments by Invited witnesses. 
5 p.m.— Dinner. 
7:30 p.m — Comments by other witnesses. 
9 p.m.— Adjournment. 
Friday. December 16. 1977 
9 am— Summary and comments— Dr. Fre- 
drickson. 
9:15 am— Section IV. Roles and 
Responsibilities 
Dr. Walters 
9:45 am.— Comments by Invited witnesses. 
10:45 am— Coffee break. 
11 am— Comments by other witnesses. 
12 am— Lunch. 
1:15 pm— Committee discussion. 
5 p.m.— Adjourn sine die. 
Dated: November 15. 1977. 
Suzanne L. Fremeau, 
Committee Management Officer. 
[FR Doc. 77-33745 Filed 11-21-77: 8:45 am] 
FfDCRAl RKJUTH. VOL 42. NO. 235— TUISDAY, NOVIMMR 22. 1977 
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