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Federal Register / Vol. 52. No. 154 / Tuesday, August 11. 1987 / Notices 
container (e g. tank, aquarium, etc.). 
Acceptable barriers include appropriate 
filter, irradiation, heat treatment, 
chemical treatment, etc. Moreover, the 
top of the rearing container should be 
covered to avoid escape of the organism 
and its gametes. In the event of tank 
rupture, leakage, or overflow, the 
construction of the room containing 
these tanks should prevent the 
organisms and gametes from entering 
the building's drains before the 
organism and its gametes have been 
inactivated.” 
339. “Other types of non-laboratory 
animals may be accommodated by 
laboratory Biosafety levels 1 to 4 
specified in Appendix G or Biosafety 
Levels 1-3 for plants described in 
Appendix P. Examples might include 
certain nematodes, insects and certain 
forms of smaller animals." 
340. “It is proposed that the following 
new footnote, number 7. be added to 
Appendix B-IV. Footnotes and 
References of Appendix B " 
341. “(7] The containment 
requirements for derivatives of 
pathogenic strains that are attenuated 
by deletion or other means that prevent 
reversion to pathogenicity can be 
lowered by the 1BC.” 
OMB's "Mandatory Information 
Requirements for Federal Assistance 
Program Announcements" (45 FR 39592) 
requires a statement concerning the 
official government programs contained 
in the Catalog of Federal Domestic 
Assistance. Normally NIH lists in its 
announcements the number and title of 
affected individual programs for the 
guidance of the public. Because the 
guidance in this notice covers not only 
virtually every’ NIH program but also 
essentially every Federal research 
program in which DNA recombinant 
molecule techniques could be used, it 
has been determined to be not cost 
effective or in the public interest to 
attempt to list these programs. Such a 
list would likely require several 
additional pages. In addition NIH could 
not be certain that every Federal 
program would be included as many 
Federal agencies, as well as private 
organizations, both national and 
international, have elected to follow the 
NIH Guidelines. In lieu of the individual 
program listing. NIH invites readers to 
direct questions to the information 
address above about whether individual 
Programs listed in the Catalog of 
Federal Domestic Assistance are 
affected. 
Dated: August 5. 1987. 
lames C. Hill, 
Acting Director. National Institute of Allergy 
and Infectious Diseases. 
(FR Doc 87-18201 Filed 8-10-87; 8:45 am) 
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