CALL TO ORDER AND INTRODUCTORY REMARKS. 
I . 
Dr. McGarrity, Chair, called the meeting of the Recombinant DNA 
Advisory Committee (RAC) of the National Institutes of Health 
(NIH) to order at 9:00 a.m., June 3, 1988. He said the meeting 
was called pursuant to a Federal Register notice which, being 30 
or more days prior to today's date, met requirements of the NIH 
Guidelines for Research Involving Recombinant DNA Molecules. He 
stated that the meeting would remain open to the public for its 
entirety, and that he expected the meeting to conclude within one 
day. 
Dr. McGarrity asked Dr. Gartland if a quorum was present and 
Dr. Gartland assured the Chair that a quorum was in attendance. 
Dr. McGarrity noted that he intended to make every effort to 
abide by the distributed agenda with respect to time estimates 
for each item of business. He reminded the committee that in 
recognizing persons for comments he would use the following 
order: primary and secondary reviewers on each item as set forth 
in the agenda; other members of RAC; ad hoc consultants to the 
RAC; NIH staff members; members of the public who had submitted 
written comments; and finally, other members of the public. He 
underlined that RAC was advisory to the Director of NIH; and in 
light of this, persons with minority opinions should voice them 
so as to provide Dr. Wyngaarden with the entire spectrum of 
opinions on a given topic. Dr. McGarrity then told the committee 
that in all voting he would call first for the affirmative, then 
for the negative, and finally for abstentions. He underlined 
that if any voting member felt compelled to abstain due to 
conflict of interest, that such member should notify the Chair so 
that the record could duly reflect such. 
Dr. McGarrity then made note of Mailings I and II which were sent 
to members prior to the meeting. He also noted that some 
recently received materials were supplied at the table for each 
member. Further, he said because of a scheduling conflict Item 
Number IX would be taken out of order and discussed immediately 
following the luncheon recess. 
Dr. McGarrity welcomed the following new members present at their 
first meeting: Dr. Ronald Atlas, Mr. Michael Brewer, Dr. James 
Childress, Dr. Martin Gellert, Mr. Brian Mannix, Mr. Robert 
McCreery, Dr. Scott Mclvor, Dr. Richard Mulligan, Dr. Robert 
Murray and Dr. Monica Riley. 
As Dr. McGarrity was technically a new member, he introduced 
himself to the committee and thanked his predecessors, in 
particular Ray Thornton, Kenneth Burns, and Robert Mitchell for 
their advice since his recent appointment as Chair. He said he 
was honored and privileged to serve as Chairman of such a 
distinguished group. He said he had served as both a member and 
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