Dr. Pramer said that he would like more information on the 
Argentine situation. Dr. Cohen said further information is 
really not needed. The basic point is that the Argentine 
government was in a position in which it could say that it knew 
nothing about the ongoing research. 
Dr. Cohen suggested that the subcommittee focus on the language 
drafted by Dr. Susan Gottesman of the NIH at the June 3, 1983, 
RAC meeting (Attachment II). Mr. Lanman said that 
Dr. Gottesman 's proposal may go beyond what the subcommittee 
wishes to cover. More precise language regarding "direct 
extension" is needed or the proposal could result in covering all 
transfer of research materials. He noted that certain 
obligations could be imposed on a recipient, but that a recipient 
could provide the material to a third party without imposing the 
conditions . 
There was discussion of the definition of "collaboration," 
"direct extension," "control," and "next logical step." Drs. 
Pramer and Riley reiterated that it will be impossible to cover 
every conceivable situation. There was discussion of using 
"collaborative effort" vs. "control." Dr. Riley said that 
"control" will cover fewer situations as a collaborator does not 
necessarily control the actions of another collaborator. 
Dr. Pramer raised the situation in which a principal investigator 
is finished with a project and enters into a contractual 
arrangement rather than a collaborative agreement. 
Dr. Korwek suggested including the notion of "collaboration" and 
"control" Dr. Pramer pointed out that there are situations in 
which there is "control" without "collaboration." Dr. Atlas 
pointed out that some providers of materials require a 
collaboration. Dr. Pramer suggested using "influence" rather 
than "control." Dr. Vidaver suggested that direct provision of 
research materials could be specifically exempted. She also 
suggested using "oversight" rather than "control." Dr. Davis 
suggested the word "involvement. He said the main point is not 
to inhibit the exchange of research materials. 
After further discussion and editing of proposed language, the 
subcommittee recommended that the following proposed amendment of 
Section I-C be published for comment: 
"The NIH Guidelines are also applicable to recombinant DNA 
projects done abroad: 
"1. if they are supported by NIH funds; or 
"2. if they involve deliberate release into the environment 
or testing in humans of materials containing 
Recombinant DNA Research, Volume 13 
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