M Kucnn ci al.: S~i(c tin noth rvologv 
Annex 3. Comparison of EFU Class 3 with corresponding national 
descriptions 
National description 
EFD description 
The Netherlands (3) 
Capable of causing severe ill* 
ness at large listed as Gass 
II 
Similar but includes effect on 
population. Mentions prophy- 
laxis and treatment 
United States (3) 
Agents of high potential risk to 
personnel and the environ- 
ment 
Similar but mentions that ef- 
fective prophylaxis and treat- 
ment are available 
Germany (4) 
Constitute a severe risk to lab- 
oratory workers. There is some 
risk to vicinity and an unknown 
risk to animals 
Similar but mentions that ef- 
fective prophylaxis and treat- 
ment are available 
United Kingdom (7) 
Biological agents that may 
cause severe human disease; 
they are a serious hazard to 
laboratory workers. May pre- 
sent a risk of spread in the 
community but effective pro- 
phylaxis and/or treatment are 
available 
Virtually the same as UK 
Croup 3. All relevant aspects 
are mentioned 
Annex 4. Comparison of EFU Cl; 
descriptions 
i\s 4 with corresponding national 
National description 
EFB description 
The Netherlands (3) 
Microorganisms that are highly 
pathogenic to man and ani- 
mals. Are a threat to the envi- 
ronment (man and animals). 
There is no biological protec- 
tion. Netherlands Gass III 
Virtually the same Dutch Gass 
lit 
Germany (4) 
Microorganisms that arc a 
severe threat to laboratory 
workers. There is a severe and 
unknown risk to the sur- 
rounding population and ani- 
mals 
Similar but mentions lack of 
prophylaxis and treatment 
United States (6) 
Microorganisms that are ex- 
tremely hazardous to labora- 
tory personnel. May be exotic. 
Isolation of workers and labo- 
ratory essential 
Similar but mentions lack of 
prophylaxis and treatment 
United Kingdom (7) 
Biological agents that cause 
human disease and which are a 
serious threat to laboratory 
workers. Present a high risk of 
spread in the community. 
Usually no effective prophylax- 
is or treatment are available 
Virtually tame as UK Croup 4 
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