Thank you for your attention to this matter and for your demonstrated 
ccrrmitirent to the thoughtful deliberations of the RAC. Please conmunicate 
my appreciation to Dr. Walters and the members of the Human Gene Therapy 
Subconmittee for their efforts to provide constructive recommendations to 
the RAC. 
Sincerely, 
James B. Wyngaarden, M.D. 
Director 
Recombinant DNA Research, Volume 13 
[443] 
