NOTICES 
27941 
(i) The color of material on which the label 
is printed must be white and the symbol and 
printing in red. 
(ii) The label must be a rectangle meas- 
uring 51 mm. (2 inches) high by 102.5 mm. 
(4 inches) long. 
(iii) The red symbol measuring 38 mm. 
( 1 1/ 2 inches) in diameter must be centered 
in a white square measuring 51 mm. (2 
Inches) on each side. 
(iv) Type size of the letters of label shall 
be as follows: 
ETIOLOGIC AGENT 10 pt. rev. 
BIOMEDICAL MATERIAL 14 pt. 
IN CASE OF DAMAGE OR , 
LEAKAGE 10 pt. rev. 
NOTIFY DIRECTOR CDC AT- 
LANTA, GA 8 pt. rev. 
404 633 5313 10 pt. rev. 
(5) Damaged packages. Carriers shall 
promptly, upon discovery of damage to the 
package that indicates damage to the pri- 
mary container, isolate the package and no- 
tify the Director, Center for Disease Control. 
1600 Clifton Road NE„ Atlanta, GA 30333 
(telephone (404) 633-5313), and the sender. 
(6) Registered mail or equivalent system. 
Transportation of the following etiologic 
agents shall be by registered mail or an 
equivalent system which requires or provides 
for sending notification to the shipper imme- 
diately upon delivery : 
Actinobacillus mallet. 
Coccidioides immitis. 
Francisella (Pasteurella) tularensis. 
Hemorrhagic fever agents, including, but not 
limited to, Crimean hemorrhagic fever 
(Congo), Junin. Machupo viruses. 
Herpesvirus simiae (B virus). 
Histoplasma capsulo.tum. 
Lassia virus. 
Marburg virus. 
Pseudomonas pseudomallei. 
Tick-borne encephalitis virus complex. In- 
cluding, but not limited to, Russian spring- 
summer encephalitis, Kyasanur forest dis- 
ease, Omsk hemorrhagic fever, and Central 
European encephalitis viruses, Variola 
minor and Variola major. 
Yersenia (Pasteurella) pestis. 
(d) Notice of delivery; failure to receive 
When notice of delivery of agents containing, 
or suspected of containing, etiologic agents 
listed in paragraph (c) (6) of this section is 
not received by the sender within 5 days fol- 
lowing anticipated delivery of the package, 
the shipper shall notify the Director; Center 
for Disease Control, 1600 Clifton Road NE., 
Atlanta, GA 30333 (telephone (404) 633- 
5313). 
(e) Requirements; variations. The Ad- 
ministrator may approve variations from 
the requirements of this section if, upon re- 
view and evaluation, he finds that such varia- 
tions provide protection at least equivalent 
to that provided by compliance with the re- 
quirements specified in this section and 
makes such findings a matter of official 
record. 
(Sec. 361, 58 Stat. 703; 42 U.S.C. 264) 
(FR Doc .72-9887 Filed 6-29-72:8:46 am] 
PACKAGING AND 
LABELING OF 
ETIOLOGIC 
AGENTS 
Th? Inle/it.ite ClM.iruMtint Reguljjioni 142 CFfl. P.n t 72 ?*.» 
Etiologic Agents) writ reviled July 31. 19/2 Id piovultf l<* 
packaging and labeling requirements lor etiologic .ii/ritt*, ui.d 
certain other materials shipped in interstate lioffic. 
Figures 1 and 2 diagram the packaging and labeling of elm 
logic agents in volumes of less than GO ml. in accordance with 
the provisions ol subparagraph (C) (1) ol the cited regulation. 
Figure 3 illustrates the color and sire of the lalrel. described 
in subparagraph (C) (4) of the regulations, winch shall l>e 
alined to all shipments of etiologic agents. 
For further ifibsrnifit .M on any provision of this rcgulalioii 
contact ; 
Center for Disease Control 
Attn: Biohazards Control GffiCi 
1600 Clifton Road’ 
Atlanta, Guuiyi.t 30333 
Tdi-phi >nc: 404 CJ3 3-II1 
FIGURE 3 
ETIOLOGIC AGENTS 
BIOMEDICAL 
MATERIAL 
IN CASE OF DAMAGE 
- OR LEAKAGE 
X NOTiry, {jtr.^CTO«.^.or 
- f ’ ATLANTA. o‘lOROA 
404/631531 3* ' V 
PACKAGING AND LABELING OF ETIOLOGIC AGENTS 
ABSORBENT PACKING MATERIAL 
PRIMARY CONTAINER (Bottle, blood bug. etc.)’ 
•NOTE: Single primary containers rruy not exceed S00 
ml. of material. Two or more primary containers whose 
combined volumes do not exceed 500 mt. may be en- 
closed in a single, secondary container. The maximum 
volume of etiologic agent which may be enclosed in a 
single outer shipping container shall not exceed 4000 ml.. 
SHOCK ABSORBENT MATERIAL 
SECONDARY CONTAINER (Gasketed screwcap 
with waterproof tape or hermetically sealed can) 
OUTER SHIPPING CONTAINER 
MAILING LABEL 
ETIOLOGIC AGENT LABEL 
The Interstate Quarantine Regulations (42 CFR, Pact 
72.25, Etiologic Agents) was revised |uly 3t, 1972, to 
provide for packaging and labeling requirements for dia- 
logic agents and certain other materials shipped in inter- 
state traffic. The illustration shows acceptable packaging 
and labeling of etiologic agents in accordance with sub- 
paragraphs (c) (2) and (4) of the cited regulation. 
For further information on any provision of this regulation contact: 
Center for Disease Control 
Attn: 8iohazards Control Office 
1600 Clifton Road 
Atlanta, Georgia 30333 
Effective July 30, 1972 
Telephone 404-633 331 1 
, NO. 131 — WEDNESDAY, JULY 7, 1976 
[ 41 ] 
FEDERAL REGISTER, VOL. 41 
