Dr. Fredrickson received extensive correspondence from participants 
and other parties. The correspondence appears in this volume after 
the conference proceedings. 
From the public hearing and the correspondence. Dr. Fredrickson 
selected several issues to be reviewed by the Recombinant Advisory 
Committee at its April meeting. Dr. Fredrickson's letter to the 
committee members and an accompanying document outlining the issues 
appear in the present volume. The responses of the Recombinant Advisory 
Committee were taken into account, and are detailed in the Director's 
decision paper appearing in the first section of this report. 
Special concern was expressed at the public hearing and in related 
correspondence regarding the application of the guidelines to research 
conducted outside NIH by investigators other than its grantees or 
contractors. In response to these suggestions. Dr. Fredrickson held 
a meeting with representatives of relevant HEW agencies and other 
departments of the Federal Government. The purpose was to exchange 
information on recombinant DNA research and to discuss the NIH 
guidelines. A letter of invitation to the participants, a roster of those 
attending, and a memorandum summarizing the meeting, held in 
April 1976, appear in the present volume. 
Concerns expressed by commentators about the extension of 
guidelines to the private sector led Dr. Fredrickson to hold a meeting 
in June 1976 with representatives of private industry, to provide them 
with full information about the guidelines and to help determine the 
present and future interest of industrial laboratories in this type of 
research. The meeting afforded one of the first opportunities for 
industry representatives to convene for discussion of this research 
area. The letter of invitation, a list of the participants, and a brief 
summary of that meeting are also included. 
Because of special interest by congressional staff, a briefing session 
was held on June 14 to discuss the forthcoming NIH guidelines. 
Congressional staff invited to attend this briefing session are listed 
in the present report. 
A number of documents are included that relate to the release of 
the guidelines- -the press release. Dr. Fredrickson's opening remarks 
at a press conference, and selected press articles. In response to 
public interest in a broad dissemination of the guidelines, a number of 
documents are included that indicate the extensive distribution nationally 
and internationally. Also included are representative letters sent to 
professional organizations soliciting support for the guidelines among 
their member scientists and to editors of journals requesting editorial 
endorsement. Lists of the organizations and journal editors receiving 
letters are enclosed. Finally, a bibliography of selected review 
articles on recombinant DNA research is provided. 
x 
