143 
DR. FREDRICKSON: Mr. Hutt? 
MR. HUTT: Dr. Brown, as I understand you, it seems to me that there 
are two possibilities here. One would be in terms of the flexibility we 
desire and that Dr. Koshland mentioned a short while before. One would be 
in a sense an ad hoc variation from the rules by an individual laboratory 
for good reason, that they advance and which might be agreed to by the 
advisory committee. 
The other is for amendment of the rules that would apply across the 
board there. Now, would you feel more comfortable and others in the room 
who are concerned about the flexibility issue, if procedures were incor- 
porated in the rules, and I agree with you, they are rules, not just 
guidelines, that would specifically provide a mechanism for that to happen? 
DR. BROWN: Oh, by all means. I much prefer the notion that I as an 
experimentalist can go to some committee, present my physical, ecological 
containment experiments I wish to do, and have them judge it individually 
rather than have some blanket ruling irrespective of the manner in which 
I do my experiments. I much prefer that kind of arrangement. 
Why, even in the human experimentalist category they are premitted to 
give an airing to their experiments. 
DR. FREDRICKSON: Thank you very much. Dr. Brown. 
Dr. Silverstone, you still have five minutes remaining of your original 
time. Did you wish to use it? 
(Laughter. ) 
Well, five and a half. Dr. Silverstone is from MIT, as he reminded me 
earlier. 
DR. SILVERSTONE: I hope the committee's endurance is as good as our 
latest cross-country ski winner, because it has been a long afternoon. 
I am a member and participant of several groups, including the recom- 
binant DNA group of the Boston Area. The other groups were the Genetics 
and Society Group of Science for the People, which sent you a mailing con- 
cerning certain other issues, and a group at MIT, an ad hoc group of bio- 
logical workers that have formed a health and safety committee. It is 
composed of technicians and laboratory assistants, representatives of the 
trade unions including the custodial unions, students, post-docs, and 
faculty members. 
The concern of these groups is not abstract with these guidelines. 
The members of these groups are among the first to be exposed, and like 
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