183 
It should be signed. It should be available. All the names of the investi- 
gators should be known to the public, and that the principal investigator 
and the institution share responsibility for the eventuality of damage 
being done. 
I am concerned about informed consent, particularly for all of the 
people that are associated with the laboratories, the secretaries that enter 
the labs, the janitors, et cetera. I don't mean to be reversibly chauvinis- 
tic, but I think that there is some argument to be made for male technicians 
in this work rather than female, because of the danger of _E. coli infections 
in the urinary tract during pregnancy, and I think that these sorts of 
things should be considered. Certainly any woman in the reproductive age 
should be warned of hazards to a fetus as well as to herself. 
I think the local biohazard safety committees, the institutional review 
committees, and the peer review committees should also be carefully reviewed 
in terms of what their charges are and how they would best monitor and 
survey the ongoing experiments. 
DR. FREDRICKSON: Thank you. 
Dr. Handler? 
DR. HANDLER: Thank you. 
I have been impressed with the historic character of what you are doing 
rather than precisely what is being done. I think Dr. Shaw has just stated 
a long set of caveats which require much more discussion that you will get 
around this table today or in the next several weeks, and will require very 
careful thinking through. And that means that this process is by no means 
done. We have a long way to go in it. 
That some problem arising within the context of scientific endeavor 
should have been examined this way before the government itself decides what 
position it will take is really historic, and you are very much to be con- 
gratulated for getting as far as you have done, and I share with Judge 
Bazelon the concern with where you go next and I don't envy you that task. 
I found it very troublesome that I could sit here for a day and a half 
and seem to agree with everything that was said. 
(Laughter. ) 
Usually at least I can dismiss some part of what I have heard, but that 
wasn't so. I found myself agreeing with everyone in turn in a very real and 
sympathetic way, and that meant that I didn't know my own mind, it certainly 
indicated to me that the confusion was worse than I thought it was as I 
arrived. Dr. Stetten described it as being a contest between, I think he 
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