Page 2 - 
The participants at the February meeting were especially concerned 
that there be guidelines for DNA recombinant research not supported 
or conducted by the NIH. There was general agreement that the NIH 
should undertake to disseminate information on the guidelines as 
widely as possible to governmental agencies and the private sector 
that support recombinant research. In light of these suggestions, 
the meeting on April 8 will serve as an important beginning to 
address this public concern. I would welcome any information that 
you might have on ongoing DNA recombinant research. Further, at 
the meeting, I have arranged for a brief presentation on how the 
NIH intends to implement these guidelines. Your views on their 
applicability to your agency or other agencies and the private 
sector would be most helpful. 
I look forward to meeting you on Thursday. I have enclosed a copy 
of the agenda book that was prepared for the participants at the 
Director’s Advisory Committee meeting in February. It contains 
the initially proposed guidelines and supplementary material on 
the science of recombinant research and the potential benefits 
and hazards. 
Sincerely yours, 
/si 
Donald S. Fredrickson, M.D. 
Director 
Enclosure 
[ 419 ] 
