Because of the important but uncharted areas opened up 
by recent developments in Recombinant DNA research, the following 
procedures are recommended, to be administered by the Office of the 
Director of NIH. 
The Director shall appoint a Technical Committee on Recom- 
binant DNA, to be made up of 15 experts in the field. At the beginning, 
five will be appointed for one year, 5 for 2 years, and 5 for 3 years. 
At the end of each year 5 new members will be appointed for a 3 -year 
term. The committee will meet every 4 months. Its functions will be: 
(1) To review the current regulations (euphemistically hereto- 
fore called guidelines) and to suggest modifications as new information 
becomes available. 
(2) To plan model experiments to be carried out in the 
appropriate NIH containment facilities. These experiments will.be 
planned to yield data to determine the next steps that can safely be 
taken to advance our knowledge of Recombinant DNA. The data and their 
analysis shall be published as each forward step is taken. 
(3) To review Recombinant DNA research grant and contract 
applications submitted to NIH and to evaluate them for scientific merit 
and for adherence to safety standards. 
The Technical Committee will report to the Recombinant DNA 
Advisory Council, which serves as the policy-making body. It receives 
the reports and after deliberation recommends action to the Director of NIH. 
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