504 ANALYSIS OF CONTINENTAL JOURNALS. 
Temperature before the operation ... 36° (Centigrade) in the mass of 
the muscles. 
„ immediately after .... 36°, idem. 
Eight days after the division, May 1 6 th : — 
Right side . . . 38° in the muscles of the thigh. 
Left side . . . 37°, idem. 
Twenty-one days after, May 30th: — 
Right side . . . . 36°, 8. 
Left side .... 37°, 6. 
Thirty days after, June 10th : — 
Right side . . . . 36°, 3. 
A glance at this table is sufficient to show the excessive 
modifications in the temperature occurring from the moment 
the nerve was divided. At another time we will deduce from 
it the information it conveys, with regard to the study of the 
experimental lesion to which it is related. 
2. Examination of the other tissues besides the muscles, 
comprising the skin and its appendages, vessels, bones, &c. 
a. The Skin in general. — One of the first modifications pro- 
duced by division of the sciatic nerve, is that which is easily 
noted in the skin of the sole of the corresponding foot. 
This modification consisted essentially — at first, in a change 
of colour — relative paleness, more or less pronounced ; then 
dryness, roughness , and the formation of scales which were 
easily detached by slight scratching. These scales also be- 
came detached spontaneouly, and left exposed small bleeding 
excoriations. In a short time these superficial alterations 
were succeeded by a true ulcerative condition ; the period 
between the section of the nerve and the manifestation of 
these alterations was from six to eight days, though a practised 
eye could detect them from the fifth day. 
b. Hairy Horn , Tissue. — With the tegumentary tissue there 
coincided alterations in the hair which did not differ materially 
from those observed and described by M. Brown-Sequard. 
The hairs at the extremity of the paw lost their gloss and 
smoothness ; they became brittle, and often broke sponta- 
neously towards their root, becoming reduced by fragments, 
but not altogether disappearing; while other hairs were 
shed integrally, leaving denuded patches on the skin. 
The hair-roots offered alterations which were doubtless con- 
nected with the spontaneous destruction of the hairs. We 
shall again refer to the changes in the deeper layers of the 
skin and its vessels, but for the present we must confess that 
we have not been able to determine satisfactorily the lesions 
occurring in the hair-bulbs. 
