812 
THE FUNGOID ORIGIN OF DISEASE, ETC. 
traverse the parietes of vessels by means of their amoeboid 
movements. Kremianski and Hayem confirmed these views, 
repeating the experiments, especially on the tongue and me- 
sentery. Dr. Charlton Bastian, in this country, also adopted 
this opinion, and the name of “ migration of leucocytes” was 
given to this phenomenon. The well-known M. Vulpian 
also supported these views, finding, like M. Hayem, the 
globules lying along the vessels, and filling up the intervas- 
cular spaces. 
But in 1870 a controversy arose on the subject, and M. 
Feltz, of Strasburg, after carefully experimenting on the 
mesentery and tongue of the frog and the mesentery of the 
mouse, showed that new leucocytes formed around the 
vessels, that these leucocytes did not arise from the corpuscles 
of the connective tissue, and had in no way traversed the 
parietes of the vessels. M. Feltz resorted, like Cohnheim 
and Kremianski, to the colouring of the leucocytes with ani- 
line and cinnabar, and maintained his opinion after a second 
series of experiments, presented to the Academy of Sciences 
of Paris on June 6th, 1870. 
This physiologist w r as followed by M. Picot, of Tours, 
who, in July, 1870, also sent a paper on the subject to the 
Academy of Medicine of Paris, and proved that Cohnheim 
was wrong — so much so that, according to M. Picot (from 
whose letter in the £ Gaz. Hebd.,’ Sept. 22nd, 1871, we have 
extracted these details), the globules of pus newly formed 
' are found far from the vessels. 
M. Picot, in a few sensible remarks, shows how difficult it 
is to make out the migration above alluded to, and enters 
into minute details as to the manipulation of these experi- 
ments. He contends also that, independently of experiments, 
the fact of finding leucocytes surrounding vessels is no pre- 
sumption that they have traversed their coats. Thus stands 
the matter at present. It is to be hoped that the praise- 
worthy endeavours of the young generation of pathologists 
will ere long solve the problem. — Lancet. 
THE FUNGOID ORIGIN OF DISEASE, AND SPONTANEOUS 
GENERATION. 
By Jabez Hogg, Hon. Sec. R.M.S. 
In the report of the medical officer of the Privy Council 
just issued, the origin and pathology of contagion is ably dis- 
cussed, and the crude hypothesis of Hallier bearing upon 
this point, who, it will be remembered, sought to prove that 
