46 
Pathological Contributions. 
CANCEROUS DEPOSIT IN THE LIVER AND 
SPLEEN IN THE DOG. 
We are indebted to Messrs. Gowing and Son for the 
particulars of two remarkable cases of cancer affecting the 
internal organs of the dog. In each case the animal was 
aged, and in a hopeless condition when first seen by Messrs. 
Gowing, consequently no treatment was attempted. 
Post-mortem examination was made soon after death, and 
the appearances satisfactorily explained the condition of the 
dogs during life. 
In the first case, which was examined in the beginning of 
October, there was a large nodulated tumour, of a pale 
greyish-yellow colour at the root of the mesentery. 
Numerous deposits of a similar character were found all 
over the liver, both covering the surface, and extending to 
the interior of the gland. 
Under the microscope the deposit was found to consist of 
cells of various forms, caudate, spindle and fibre-cells, with 
many others containing nuclei, and evidently multiplying 
by the endogenous process. 
A considerable quantity of fine fibrous stroma gave to the 
deposit a density and hardness characteristic of scirrhous 
growths. There was scarcely a trace of the milky juice 
which is an invariable constituent of encephaloid tumour. 
The second animal presented appearances in some respect 
more marked than those which have just been described. 
The subject of the disease was a Maltese dog, aged fourteen 
years, which was seen by Messrs. Gowing only a few hours 
before its death. 
On post-mortem examination the liver was found to be 
covered with yellowish spots, and a tumour of similar cha- 
racter was detected in the spleen. 
Microscopic examination of the morbid deposit resulted 
in the detection of the same elements which had been 
observed in the former case. 
No history was obtained in either instance, but there can 
be no doubt that the primary deposit occurred in the mesen- 
tery in the first case, and in the spleen in the second, and 
that it was followed in both by cancerous infiltration into 
the structure of the liver. 
