INOCULATION FOR tLEURO-PNEUMONI A . 
133 
lation for pleuro-pneumonia we have a total absence of the 
manifestations apparent in other inoculations ; there are no 
local signs of its having taken, nor constitutional or febrile 
disturbance that can be detected, even though we call in the 
aid of that delicate instrument, the clinical thermometer, as 
proved by its readings in experiment No. 9, the particulars 
of which are in a tabulated form under it. 
As no opportunity has occurred of examining the lungs 
after death of inoculated animals under circumstances favor- 
able for the forming of a truthful opinion as to their condition 
it may yet be discovered that some morbid lesions , serous exudation , 
so characteristic of pleuro-pneumonia , or traces of such, may exist 
as a consequence of inoculation, and in order to put this to the 
test, as well as the whole question of the prophylactic in- 
fluence of the operation, I venture to suggest the following 
series of experiments : 
Proposed Experiment No. 1 . — That twelve young animals, 
bred on a farm where pleuro-pneumonia has not existed for 
four years, should be purchased, and inoculated, and that 
four should be slaughtered six weeks, four twelve weeks, and 
four sixteen weeks after the operation, for the purpose of 
examining minutely the cavity of the chest, pleurae, and 
lungs. 
Proposed Experiment No. 2. — That 100 young oxen, bred 
under the same conditions as in proposition No. 1, should be 
purchased, and that 50 of them should be inoculated on the 
farm; and that ten of the inoculated, and ten of the un- 
inoculated, should be sent into five infected herds, and kept 
on the premises, where practicable, for a period of from six 
to twelve months. 
Proposal No. 3. — As it is a well-known fact that certain 
farms in this country have never, for the last fourteen or 
sixteen years, been without one or more cases of pleuro- 
pneumonia occurring annually amongst the herds, that the 
proprietors of such farms shall be induced to have all fresh 
animals introduced upon them for the next four years 
inoculated. 
Before concluding this report, I beg to thank Mr. J. D. 
Overed, M.R.C.V.S., of Blofield, for the ready and valuable 
assistance he has rendered in the prosecution of the foregoing 
experiments. 
To Professor Gamgee, of London, thanks are especially 
due for the kind presentation of two clinical thermometers 
of very delicate construction, which he had regulated at 
Greenwich, before sending them for the purpose of those 
experiments. 
XLIII. 
10 
