ANALYSIS OF CONTINENTAL JOURNALS. 397 
from the blood, and the liquids and solids are soon pervaded 
by the icteric tint.” 
This view, however, the author does not take credit for, as 
several physiologists have considered the bile as an excre- 
mental product. According to M. Colin, the bile is thick 
and viscous in proportion to the secretion, being less abundant 
— which is, moreover, the case also with other secretions. 
These physiological views seem to be completely borne out 
by pathological facts ; consequent on these reflections I have 
thought it important to search for some remedy that was 
capable of restoring the function of the liver in jaundice of 
the dog. The author continues : 
“ After several attempts I fixed on the chloride of mercury 
(calomel), the purgative properties of which have been 
admitted; but after having administered this drug in purga- 
tive doses without satisfactory result, I resorted to it in altera- 
tive doses, and the results obtained have been beyond my 
expectation, so that there is no case of true jaundice of the 
cure of which I despair at present. 
Without, however, pretending to have cured every case, 
I can affirm that since I am in possession of this remedy the 
fatal termination of the malady has been very rare ; while 
before the cures were exceptional, and death the rule ; but the 
method of administration is not a matter of indifference. The 
medicine must be given in small doses three or four times a 
day, without, however, carrying it to purging. As soon as that 
supervenes, the dose must be decreased, and stopped altogether 
fora time, if the purging is violent. The dose is from five 
to ten centigrammes, to be made up in pills, given from two 
to four times a day. This is to be continued fora few days if 
purging does not set in ; if, on the other hand, purging 
occurs the dose must be reduced or suspended altogether, 
until it has stopped. 
“ The administration of the calomel in the form of pills is 
preferable, as the agent is insoluble in water, and the suspension 
in other liquids is at best unsatisfactory and uncertain; enemas 
slightly charged with laudanum are to be given in accordance 
with the indications. If the dog is able to eat, he is to be 
allowed food, avoiding all salted substances. After four or 
five days of the administration of the medicine, an abundant 
salivation set in, but I have not had this followed by inflam- 
mation of the stomach or gangrene of the mouth; in some 
cases, however, there is loosening of the teeth; this was the 
case particularly with a young terrier, which had taken the 
calomel for five days in doses of five centigrammes three 
times a day. The animal lost five teeth, but recovered of 
xliii. 27 
