ON MEDICINAL PEPSIN. 
697 
mes of coagulated egg-albumen, and twenty-five cubic centi- 
metres of distilled water, containing one per cent, of hydro- 
chloric acid, were employed. The quantities of pepsin used 
are stated in the subjoined table, which is intended to show 
the relative amounts of the different makers (A, B, C, D, E, 
F) required to digest the same quantity of albumen in four 
hours. Two comparative experiments were in every instance 
set going at the same time. 
It having been found impossible to continue the experi- 
ments w T ith make C with more than F5 gramme of pepsin, in 
consequence of the inability of 25 cubic centimetres of acidu- 
lated water to keep the mixture in a sufficiently liquid state, a 
second series of experiments was performed, in which 50 in- 
stead of 25 cubic centimetres of diluted acid were employed. 
The weight of albumen used was the same as that in the first 
series — viz., 5 grammes. 
Table showing Results of Second Series of Experiments upon 
Albumen (50 cubic centimetres of acidulated wate r ) . 
Weight of 
Pepsin 
employed in 
Grammes. 
MAKE OP PEPSIN. 
A. 
B. 
C. 
D. 
E. 
P. 
0-050 | 
0-250 
0-300 
0- 400 
0*500 
1- 000 
1-250 
5-000 
Digested 
Not 
digested 
Ditto 
Ditto 
Ditto 
Digested 
Not 
digested 
Ditto 
Ditto 
Ditto 
Ditto 
Ditto 
Digested 
Not 
digested 
Ditto 
Ditto 
Ditto 
Ditto 
Ditto 
Ditto 
Ditto 
Not 
digested 
Ditto 
Ditto 
Ditto 
Ditto 
Ditto 
Ditto 
Ditto 
Not 
digested 
Ditto 
Ditto 
Ditto 
Ditto 
Ditto 
Ditto 
Ditto 
From the results of the experiments detailed in the fore- 
going tables, it will be seen — 
1st. That, in order to effect the digestion of a given weight 
of albumen, very different quantities of the pepsin prepared 
by makers A, B, C are required. 
2nd. That taking the digestive power of C as unity, the 
digestive ratios of A, B, and C are as follows : — 
C = 1 (1’25 gramme dissolves 5 grammes of albumen.) 
B = 2-5 (0-50 „ „ „ .) 
A — 25 (0 05 „ ,, ,, .) 
sequence of the 25 grammes of acidulated water employed being insufficient 
to maintain the requisite fluidity of the mixture. 
