THE ORGANIC CELL 
85 
Physiological Relations of Nucleus and Cytoplasm. 
Claude Bernard maintained that chemical synthesis, the 
process by which organic compounds are built up, and morpho- 
logical synthesis, by which these compounds are arranged into 
an organised body, are different phases of the same pheno- 
menon, and that both are the result of nuclear activity. A few 
Hybrid Fertilisation of the Egg of Ascaris megalocephala, 
YAR. BIVALENS BY THE SPERMATOZOON OF VAR. UNIYALENS. 
A. The germ-nuclei shortly before union. B. The cleavage figure forming, 
the sperm nucleus has given rise to one chromosome { $ ) the egg nucleus to two 
( $ ). C. Two-cell stage dividing showing the three chromosomes in each cell. 
I). Twelve-cell stage, with the three distinct chromosomes still shown in the 
primordial germ-cell. (Herla.) 
experiments will suffice to prove that morphological and 
chemical synthesis are the result of nuclear action, and there- 
fore that the nucleus must be looked upon as the essential 
organ of inheritance. 
Besides experiments on unicellular forms, evidence to the 
effect that the nucleus is the organ of inheritance will be 
brought from such phenomena as mitosis, maturation, and 
fertilisation. 
Experiments on Unicellular Forms . — Evidence as regards 
the behaviour of enucleated and nucleated fragments. 
