HUMANE TREATMENT OF ANIMALS USED IN RESEARCH 39 
(i) To students of science or medicine at the place first named above, 
of the fundamental facts of physiology andlor pharmacology. 
(ii) To members of learned societies, of newly discovered physiological 
facts or facts which will be useful to them for saving or prolonging 
life or alleviating suffering .” 
(c) Persons before whom the proposed experiments are to be performed. 
' “ Students of science and medicine ; members of learned societies." 
The Home Office will require that on each occasion of the licensee’s 
intention to carry out experiments under (o)(ii) or f6)(ii) above, notice be 
given, and this will be stated in Condition No. 1 of the licence. 
(5) Certificates E, EE and F 
The purpose of these certificates is sufficiently explained above and 
in the official notes printed at the head of each certificate form. It is 
essential that the “ description of experiments to be performed ” be in 
the same terms as in the Certificate A or B with which E, EE or F are 
to be combined. E accompanies A ; EE accompanies B ; F may accom- 
pany either, or both, but in the latter case it is better to submit two F’s, 
one to go with A and one with B. 
(6) Undertaking 
In certain cases the Home Office may require some senior person to 
give an Undertaking that he will make himself responsible for the proper 
observance by the applicant of the provisions of the licence. This 
Undertaking is in set form, obtainable from the Home Office. (See 
Appendix I.) 
As a general rule an Undertaking is required on behalf of all applicants 
from overseas. The Undertaking should normally be signed by the head 
of the department in which the applicant is to carry out his experiments, 
or by some senior person with whom he will be working. 
(7) Annual Return of Experiments 
About 15th December, the Home Office sends out a form for the 
Annual Return of Experiments. This form is in the main self-explanatory, 
but the following suggestions may help (in any case of doubt reference 
should be made to the Inspector) : — 
( a ) One animal normally counts as one experiment. Certain trivial 
procedures (under Certificate A) may leave the animal at the end of 
the experiment entirely normal ; if such an animal is subsequently 
used again then it is counted as another experiment. 
(b) If an experiment involves procedures under more than one type of 
certificate, it should be shown on the return as coming under the 
certificate covering the more severe procedure. For example, an 
animal prepared by means of an operation under Certificate B and 
then injected under Certificate A counts as a single experiment under 
Certificate B. 
(c) An experiment starts at the first interference with the animal’s health, 
comfort or integrity and ends on the death of the animal, or its 
complete recovery and return to stock (this can only happen in the 
case of experiments under Certificate A). 
(d) Where an experiment is carried out by more than one licensee, it must 
be shown in the annual return as a conjoint experiment ; unless, 
13 
